Description
From Genova’s Website
- “Personalized Results Overview and Nutrient Need Overview
- Functional Imbalance Scores in areas of methylation, toxic exposure, mitochondrial dysfunction, fatty acid imbalances, and oxidative stress
- Nutrient Need Overview with recommendations for antioxidants, B-vitamins, minerals, essential fatty acids, GI support, and amino acids
- Interpretation-At-A-Glance pages provide nutritional educational support for you and your patient highlighting the function of each nutrient, cause of deficiency, complications of deficiency and food sources of the nutrient
- Organic Acids (urine)
- Malabsorption and Bacterial/ Yeast Dysbiosis Markers are metabolites produced by the gastrointestinal microbiome
- Cellular Energy & Mitochondrial Metabolites are biomarkers of carbohydrate and fatty acid metabolism, and the citric acid (Kreb’s) cycle
- Neurotransmitter Metabolites are downstream byproducts of epinephrine, norepinephrine, serotonin and dopamine
- Vitamin Markers are specific analytes used to assess functional levels of vitamin cofactors
- Toxin & Detoxification Markers relate to certain toxic metabolites and the body’s detoxification capacity
- Oxalate Markers relate to kidney stone formation, oxidative stress and metabolic dysfunction
- Oxidative Stress Markers include antioxidants glutathione (whole blood) and Coenzyme Q10 (serum), as well as the oxidative damage markers lipid peroxides and 8-OHdG (urine)
- Amino Acids (plasma or urine)
- Essential Amino Acids must be derived from dietary sources
- Nonessential Amino Acids are synthesized by the body
- Intermediary Metabolites are byproducts of amino acid metabolism
- B Vitamin Markers are involved in biochemical reactions that specifically require B vitamins
- Urea Cycle Markers are byproducts associated with nitrogen (ammonia) detoxification
- Glycine/Serine Metabolites are involved in the serine-to-choline pathway and the methylation pathways
- Dietary Peptide Related Markers can indicate incomplete protein breakdown and meat intake
- Essential and Metabolic Fatty Acids Markers (RBCs)
- Omega 3 Fatty Acids are essential for brain function and cardiovascular health and are anti-inflammatory
- Omega 6 Fatty Acids are involved in the balance of inflammation
- Omega 9 Fatty Acids are important for brain growth, nerve cell myelin, and reducing inflammation
- Saturated Fatty Acids are involved in liproprotein metabolism and adipose tissue inflammation
- Monounsaturated Fats include omega 7 fats and unhealthy trans fats
- Delta-6 Desaturase Activity assesses efficiency of this enzyme to metabolize omega 6’s and omega 3’s
- Cardiovascular Risk includes specific ratios and the Omega 3 Index
- Elemental Markers
- Nutrient Elements are direct measurements of copper and zinc (plasma), magnesium and potassium (RBC), and manganese and selenium (whole blood)
- Toxic Elements (whole blood) indicate exposure to lead, mercury, arsenic or cadmium within approximately a 90-120 day timeframe
- Add-on Vitamin D (serum) measures a total of 25-hydroxyvitamin D3 (cholecalciferol) and 25-hydroxyvitamin D2 (ergocalciferol)
- Add-on SNPs (buccal swab) include MTHFR, COMT, TNF-a, and APOE”
